Achira
People Operations Manager
San Francisco Office · Posted Sep 11, 2026
$125K – $175KAbout the role
WHY ACHIRA - Join a world-class team of scientists, researchers, and entrepreneurs building the future of drug discovery. - Partner with leadership to shape how a fast-growing company operates day-to-day. - Build and scale foundational HR systems, processes, and culture in a high-growth environment. - Operate with trust, ownership, and transparency in a mission-driven company advancing science and technology. ABOUT THE ROLE Achira is seeking an experienced, people-focused operations Manager to lead the people team for an early-stage, high-growth start-up. This role oversees the full employee experience from recruiting and onboarding to performance management, employee relations, and compliance while helping shape a positive, productive workplace culture. The ideal candidate is a strategic leadership partner as well as a trusted resource for employees at every level. KEY RESPONSIBILITIES - Manage full-cycle recruiting: job postings, recruiter relations, interviews, reference checks, and offer negotiation - Oversee onboarding and offboarding processes to ensure smooth employee transitions - Develop and administer HR policies, ensuring compliance with federal, state, and local employment laws - Manage employee relations issues, including conflict resolution, disciplinary actions, and investigations - Lead performance management processes, including reviews, goal-setting, and improvement plans in collaboration with leadership - Administer compensation and benefits programs, including open enrollment and annual review cycles - Partner with team leads and project mgmt. on workforce planning, org design, and headcount needs - Maintain and improve HR systems (HRIS), records, and reporting in coordination with third party vendor support - Engage with legal counsel on immigration issues and visa processing ultimately shifting to in-house processes - Drive employee engagement initiatives and culture-building programs in partnership with leadership - Manage training and professional development programs in partnership with leadership - Ensure health, safety, and compliance standards are met across the organization - Prepare HR metrics and reports for leadership (turnover, retention, headcount, etc.) - Oversee compliance associated with benefit plans and employee policies - Flexibility in covering administrative responsibilities outside of HR ABOUT YOU - Bachelor's degree - 5+ years of progressive HR experience, including 2+ years in a management or supervisory capacity - Strong knowledge of employment law, state requirements, HR best practices, and compliance requirements - Experience with HRIS platforms (e.g., Workday, ADP, or similar) - Excellent interpersonal, conflict-resolution, and communication skills - Proven ability to handle confidential information with discretion - Strong organizational skills and attention to detail - SHRM-CP, SHRM-SCP, PHR, or SPHR certification preferred - Highly organized and detail-oriented, with the ability to manage multiple priorities and keep operations running smoothly - Strong problem-solver who is proactive, resourceful, and able to act independently - Excellent interpersonal skills; you create a positive, welcoming environment and communicate effectively across teams - Comfortable with basic tools (Google Workspace, Slack, Notion, etc.) and not afraid to learn new skills - Hands-on and adaptable — excited to roll up your sleeves and build processes in a fast-paced, evolving environment - Mission-driven and motivated to support a team advancing drug discovery - Experience in managing employees in science, technology, or research fields - Commitment to equity and employee engagement - Experience supporting a distributed or hybrid workforce - Data-driven approach to HR decision-making
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